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Literature summary for 4.2.1.17 extracted from

  • Teufel, R.; Mascaraque, V.; Ismail, W.; Voss, M.; Perera, J.; Eisenreich, W.; Haehnel, W.; Fuchs, G.
    Bacterial phenylalanine and phenylacetate catabolic pathway revealed (2010), Proc. Natl. Acad. Sci. USA, 107, 14390-14395.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-didehydroadipyl-CoA + H2O Pseudomonas sp.
-
(3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O Pseudomonas putida
-
(3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O Escherichia coli
-
(3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O Pseudomonas sp. Y2
-
(3S)-3-hydroxyadipyl-CoA
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli P76082 gene paaF encoded in the paa gene cluster
-
Pseudomonas putida
-
gene paaF encoded in the paa gene cluster
-
Pseudomonas sp.
-
gene paaF encoded in the paa gene cluster
-
Pseudomonas sp. Y2
-
gene paaF encoded in the paa gene cluster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-didehydroadipyl-CoA + H2O
-
Pseudomonas sp. (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O
-
Pseudomonas putida (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O
-
Escherichia coli (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O substrate and product identification by mass spectrometry Pseudomonas sp. (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O substrate and product identification by mass spectrometry Pseudomonas putida (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O substrate and product identification by mass spectrometry Escherichia coli (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O
-
Pseudomonas sp. Y2 (3S)-3-hydroxyadipyl-CoA
-
r
2,3-didehydroadipyl-CoA + H2O substrate and product identification by mass spectrometry Pseudomonas sp. Y2 (3S)-3-hydroxyadipyl-CoA
-
r

Synonyms

Synonyms Comment Organism
2,3-dehydroadipyl-CoA hydratase
-
Pseudomonas sp.
2,3-dehydroadipyl-CoA hydratase
-
Pseudomonas putida
2,3-dehydroadipyl-CoA hydratase
-
Escherichia coli
More PaaF is a member of the crotonase superfamily Pseudomonas sp.
More PaaF is a member of the crotonase superfamily Pseudomonas putida
More PaaF is a member of the crotonase superfamily Escherichia coli
PaaF
-
Pseudomonas sp.
PaaF
-
Pseudomonas putida
PaaF
-
Escherichia coli

General Information

General Information Comment Organism
metabolism the enzyme catalyzes a reaction step of the beta-oxidation, as part of the catabolic gene cluster for phenylacetate degradation, overview Escherichia coli
metabolism the enzyme catalyzes a reaction step of the beta-oxidation, overview Pseudomonas sp.
metabolism the enzyme catalyzes a reaction step of the beta-oxidation, overview Pseudomonas putida