Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharopolyspora spinosa | Q9ALN6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose | - |
Saccharopolyspora spinosa | dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O | enzymes SpnO and SpnN are the 2,3-dehydratase and 3-ketoreductase, which together catalyze the conversion of dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose to 4-dehydro-2,6-dideoxy-D-glucose | ? |
Synonyms | Comment | Organism |
---|---|---|
spnO | - |
Saccharopolyspora spinosa |
General Information | Comment | Organism |
---|---|---|
physiological function | in forosamine biosynthesis, enzymes SpnO and SpnN function as a 2,3-dehydrase and a 3-ketoreductase, respectively. The two enzymes act sequentially to catalyze C-2 deoxygenation of TDP-4-dehydro-6-deoxy-D-glucose to form the SpnQ substrate, TDP-4-dehydro-2,6-dideoxy-D-glucose | Saccharopolyspora spinosa |