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Literature summary for 4.2.1.145 extracted from

  • Ju, J.; Ozanick, S.G.; Shen, B.; Thomas, M.,G.
    Conversion of (2S)-arginine to (2S,3R)-capreomycidine by VioC and VioD from the viomycin biosynthetic pathway of Streptomyces sp. strain ATCC11861 (2004), Chembiochem, 5, 1281-1285.
    View publication on PubMed
Search for more literature for 4.2.1.145

Cloned(Commentary)

Cloned (Comment) Organism
overproduced in Escherichia coli with an N-terminal hexahistidine affinity tag Streptomyces sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2S,3S)-3-hydroxyarginine Streptomyces sp.
-
 (2S,3R)-capreomycidine
-
 ?
(2S,3S)-3-hydroxyarginine Streptomyces sp. ATCC 11861
-
 (2S,3R)-capreomycidine
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces sp.
-
-
-
Streptomyces sp. ATCC 11861
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptomyces sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2S,3S)-3-hydroxyarginine
-
 Streptomyces sp. (2S,3R)-capreomycidine
-
 ?
(2S,3S)-3-hydroxyarginine
-
 Streptomyces sp. ATCC 11861 (2S,3R)-capreomycidine
-
 ?

Synonyms

Synonyms Comment Organism
VioD
-
 Streptomyces sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Streptomyces sp.

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Streptomyces sp.