Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Aspergillus parasiticus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | enzyme distributes throughout the cytoplasm and concentrates in ring-like structures surrounding nuclei | Aspergillus parasiticus | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
72000 | - |
x * 72000, and x * 78000, SDS-PAGE | Aspergillus parasiticus |
78000 | - |
x * 72000, and x * 78000, SDS-PAGE | Aspergillus parasiticus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus parasiticus | Q12062 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | highest abundance of enzyme in colony fraction S2 consisting of cells that have grown for 24-48 h | Aspergillus parasiticus | - |
conidiophore | asexual developmental structures | Aspergillus parasiticus | - |
hypha | vegetative hyphae | Aspergillus parasiticus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
versiconal | i.e. (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione | Aspergillus parasiticus | versicolorin B + H2O | (3aR,12bS)-8,10,12-trihydroxy-1,2,3a,12b-tetrahydroanthra[2,3-b]furo[3,2-d]furan-6,11-dione | ? |
Subunits | Comment | Organism |
---|---|---|
? | x * 72000, and x * 78000, SDS-PAGE | Aspergillus parasiticus |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme catalyzes bisfuran ring closure in versiconal hemiacetal to form versicolorin B. This reaction is required for the subsequent activation to aflatoxin B1-8,9 epoxide, a highly reactive and toxic aflatoxin metabolite | Aspergillus parasiticus |