Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Aspergillus parasiticus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus parasiticus | - |
- |
- |
Aspergillus parasiticus NIAH-26 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | racemic versiconal hemiacetate or racemic versiconal leads exclusively to formation of (1'R,2'S)-(-)-versicolorin B. Only (1'R,2'S)-(-)-versicolorin B, and not (1'S,2'R)-(+)antipode, serves as a substrate for desaturase activity in the following reaction of the aflatoxin biosynthetic pathway. Thus the stereoconfiguration of bis-furan moiety in aflatoxin molecules is determined by the cyclase enzyme catalyzing the reaction from versiconal to versicolorinB. Nonenzymatic racemization in both the (2'R)- and (2'S)-versiconal hemiacetate enantiomers is dependent upon the temperature and alkaline conditions | Aspergillus parasiticus | ? | - |
? | |
additional information | racemic versiconal hemiacetate or racemic versiconal leads exclusively to formation of (1'R,2'S)-(-)-versicolorin B. Only (1'R,2'S)-(-)-versicolorin B, and not (1'S,2'R)-(+)antipode, serves as a substrate for desaturase activity in the following reaction of the aflatoxin biosynthetic pathway. Thus the stereoconfiguration of bis-furan moiety in aflatoxin molecules is determined by the cyclase enzyme catalyzing the reaction from versiconal to versicolorinB. Nonenzymatic racemization in both the (2'R)- and (2'S)-versiconal hemiacetate enantiomers is dependent upon the temperature and alkaline conditions | Aspergillus parasiticus NIAH-26 | ? | - |
? | |
versiconal | i.e. (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione | Aspergillus parasiticus | (-)-versicolorin B + H2O | (3aR,12bS)-8,10,12-trihydroxy-1,2,3a,12b-tetrahydroanthra[2,3-b]furo[3,2-d]furan-6,11-dione | ? | |
versiconal | i.e. (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione | Aspergillus parasiticus NIAH-26 | (-)-versicolorin B + H2O | (3aR,12bS)-8,10,12-trihydroxy-1,2,3a,12b-tetrahydroanthra[2,3-b]furo[3,2-d]furan-6,11-dione | ? |