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Literature summary for 4.2.1.127 extracted from

  • Lueddeke, F.; Harder, J.
    Enantiospecific (S)-(+)-linalool formation from beta-myrcene by linalool dehydratase-isomerase (2011), Z. Naturforsch. C, 66, 409-412.
    View publication on PubMed
Search for more literature for 4.2.1.127

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-myrcene + H2O Castellaniella defragrans
-
 (3S)-linalool
-
 ?
beta-myrcene + H2O Castellaniella defragrans 65Phen
-
 (3S)-linalool
-
 ?

Organism

Organism UniProt Comment Textmining
Castellaniella defragrans E1XUJ2 i.e. Alcaligenes defragrans, gene ldi
-
Castellaniella defragrans 65Phen E1XUJ2 i.e. Alcaligenes defragrans, gene ldi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-myrcene + H2O
-
 Castellaniella defragrans (3S)-linalool
-
 ?
beta-myrcene + H2O stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene Castellaniella defragrans (3S)-linalool (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected ?
beta-myrcene + H2O
-
 Castellaniella defragrans 65Phen (3S)-linalool
-
 ?
beta-myrcene + H2O stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene Castellaniella defragrans 65Phen (3S)-linalool (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected ?
additional information the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene Castellaniella defragrans ?
-
 ?
additional information the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene Castellaniella defragrans 65Phen ?
-
 ?

Synonyms

Synonyms Comment Organism
LDI
-
 Castellaniella defragrans
ldi/LDI
-
 Castellaniella defragrans
linalool dehydratase-isomerase
-
 Castellaniella defragrans

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Castellaniella defragrans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
 assay at Castellaniella defragrans

General Information

General Information Comment Organism
metabolism the bifunctional linalool dehydratase-isomerase ldi/LDI is the initial enzyme in the anaerobic beta-myrcene degradation pathway and catalyzes the hydration of beta-myrcene to (S)-(+)-linalool and its isomerization to geraniol. A high-affinity geraniol dehydrogenase geoA/GeDH and a geranial dehydrogenase geoB/GaDH contribute to the formation of geranic acid Castellaniella defragrans