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Literature summary for 4.2.1.125 extracted from

  • Liang, Y.; Zhao, S.; Xu, L.; Zhang, X.
    Heterologous expression of dammarenediol synthase gene in an engineered Saccharomyces cerevisiae (2012), Lett. Appl. Microbiol., 55, 323-329.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in an engineered strain of Saccharomyces cerevisiae strain 31147 from vector pAUR123, the enzyme is contained in microsomes, lipid particles, and total yeast homogenate Panax ginseng

Localization

Localization Comment Organism GeneOntology No. Textmining
lipid particle
-
Panax ginseng
-
-
membrane transmembrane enzyme Panax ginseng 16020
-
microsome
-
Panax ginseng
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O Panax ginseng
-
dammarenediol II
-
?

Organism

Organism UniProt Comment Textmining
Panax ginseng Q08IT1
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinnat enzyme from Saccharomyces cerevisiae strain 31147 lipid particles, solubilization by Triton X-100 Panax ginseng

Source Tissue

Source Tissue Comment Organism Textmining
hairy root
-
Panax ginseng
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
-
Panax ginseng dammarenediol II
-
?

Synonyms

Synonyms Comment Organism
dammarenediol synthase
-
Panax ginseng

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the first step in biosynthetic pathway of ginsenosides, overview Panax ginseng