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Literature summary for 4.2.1.125 extracted from

  • Han, J.Y.; Kwon, Y.S.; Yang, D.C.; Jung, Y.R.; Choi, Y.E.
    Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng (2006), Plant Cell Physiol., 47, 1653-1662.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
methyl jasmonate up-regulation of enzyme expression Panax ginseng

Protein Variants

Protein Variants Comment Organism
additional information expression in Saccharomyces cerevisiae mutant lacking lanosterol synthase results in production of dammarenediol and hydroxydammarenone. Silencing of gene expression by RNAi leads to a reduction of ginsenoide production to 84.5% in roots Panax ginseng

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
88400
-
x * 88400, calculated Panax ginseng

Organism

Organism UniProt Comment Textmining
Panax ginseng Q08IT1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower bud higher expression compared with root, leaf and petiole Panax ginseng
-
leaf higher expression in flower bud compared with root, leaf and petiole Panax ginseng
-
petiole higher expression in flower bud compared with root, leaf and petiole Panax ginseng
-
root higher expression in flower bud compared with root, leaf and petiole Panax ginseng
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-2,3-oxidosqualene + H2O
-
Panax ginseng (20S)-dammarenediol + hydroxydammarenone
-
?

Subunits

Subunits Comment Organism
? x * 88400, calculated Panax ginseng

Synonyms

Synonyms Comment Organism
dammarenediol synthase
-
Panax ginseng