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Literature summary for 4.2.1.12 extracted from

  • Patra, T.; Koley, H.; Ramamurthy, T.; Ghose, A.C.; Nandy, R.K.
    The Entner-Doudoroff pathway is obligatory for gluconate utilization and contributes to the pathogenicity of Vibrio cholerae (2012), J. Bacteriol., 194, 3377-3385.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-phospho-D-gluconate Vibrio cholerae serotype O1
-
2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O
-
?

Organism

Organism UniProt Comment Textmining
Vibrio cholerae serotype O1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-phospho-D-gluconate
-
Vibrio cholerae serotype O1 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O
-
?

Synonyms

Synonyms Comment Organism
6-phosphogluconate dehydratase
-
Vibrio cholerae serotype O1
EDD
-
Vibrio cholerae serotype O1

General Information

General Information Comment Organism
malfunction deletion of the edd gene results in an increased ability of the mutant to produce biofilm Vibrio cholerae serotype O1