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Literature summary for 4.2.1.12 extracted from

  • Kim, H.J.; Nam, H.S.; Anderson, A.J.; Yang, K.Y.; Cho, B.H.; Kim, Y.C.
    Mutation in the edd gene encoding the 6-phosphogluconate dehydratase of Pseudomonas chlororaphis O6 impairs root colonization and is correlated with reduced induction of systemic resistance (2007), Lett. Appl. Microbiol., 44, 56-61.
    View publication on PubMed
Search for more literature for 4.2.1.12

Activating Compound

Activating Compound Comment Organism Structure
additional information transcription of the edd gene is higher in media containing glucose than with organic acids Pseudomonas chlororaphis

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli, mutagenesis of the edd gene of Pseudomonas chlororaphis O6 encoding 6-phosphogluconate dehydratase, influence of different carbon sources on its expression and on bacterial growth analyzed Pseudomonas chlororaphis

Inhibitors

Inhibitors Comment Organism Structure
additional information transcription of the edd gene and bacterial growth is lower if succinate is the sole carbon source, the edd mutant of Pseudomonas chlororaphis O6 fails to grow on glucose media Pseudomonas chlororaphis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-phospho-D-gluconate Pseudomonas chlororaphis Entner-Doudoroff pathway 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
-
 ?
6-phospho-D-gluconate Pseudomonas chlororaphis O6 Entner-Doudoroff pathway 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
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 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas chlororaphis Q1PAG1 rhizobacterium, wild-type and mutants of the edd gene encoding 6-phosphogluconate dehydratase
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Pseudomonas chlororaphis O6 Q1PAG1 rhizobacterium, wild-type and mutants of the edd gene encoding 6-phosphogluconate dehydratase
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Source Tissue

Source Tissue Comment Organism Textmining
root rhizophere of Nicotiana tabacum Xanthi hosts the rhizobacterium Pseudomonas chlororaphis O6, effects of 6-phosphogluconate dehydratase on root colonisation and induction of systemic resistance by Pseudomonas chlororaphis 06 analyzed Pseudomonas chlororaphis
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 effects of different carbon sources on expression and growth studied in wild-type bacteria and in mutans deficient of 6-phosphogluconate dehydratase, late-stage root colonisation affected, 6-phosphogluconate dehydratase involved in maintainance of Pseudomonas populations in the rhizospere Pseudomonas chlororaphis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-phospho-D-gluconate Entner-Doudoroff pathway Pseudomonas chlororaphis 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
-
 ?
6-phospho-D-gluconate mutants deficient of 6-phosphogluconate dehydratase grow on succinate but not on glucose, role of 6-phosphogluconate dehydratase in metabolism during root colonisation and induction of systemic resistance Pseudomonas chlororaphis 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
-
 ?
6-phospho-D-gluconate Entner-Doudoroff pathway Pseudomonas chlororaphis O6 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
-
 ?
6-phospho-D-gluconate mutants deficient of 6-phosphogluconate dehydratase grow on succinate but not on glucose, role of 6-phosphogluconate dehydratase in metabolism during root colonisation and induction of systemic resistance Pseudomonas chlororaphis O6 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
-
 ?

Synonyms

Synonyms Comment Organism
6-phosphogluconate dehydratase
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 Pseudomonas chlororaphis