Literature summary for 4.2.1.118 extracted from

Eudes, A.; Sathitsuksanoh, N.; Baidoo, E.E.; George, A.; Liang, Y.; Yang, F.; Singh, S.; Keasling, J.D.; Simmons, B.A.; Loque, D.
Expression of a bacterial 3-dehydroshikimate dehydratase reduces lignin content and improves biomass saccharification efficiency (2015), Plant Biotechnol. J., 13, 1241-1250 .

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Cloned(Commentary)

Cloned (Comment)	Organism
gene qsuB, recombinant expression of the 3-dehydroshikimate dehydratase from Corynebacterium glutamicum in Arabidopsis thaliana transgenic C4H::qsuB lines, the enzyme is targeted to the plastids via plastid-targeting signal peptide (SCHL), reduces lignin content and improves biomass saccharification efficiency, reduction of lignin deposition. Compared to wild-type plants, lines expressing QsuB contain higher amount of protocatechuate, p-coumarate, p-coumaraldehyde and p-coumaryl alcohol, and lower amounts of coniferaldehyde, coniferyl alcohol, sinapaldehyde, and sinapyl alcohol. Metabolite analysis of C4H::qsuB lines, overview. Recombinant expression of YFP-tagged enzyme in plastids of transgenic Arabidopsis thaliana	Corynebacterium glutamicum

Cloned (Comment)

Organism

gene qsuB, recombinant expression of the 3-dehydroshikimate dehydratase from Corynebacterium glutamicum in Arabidopsis thaliana transgenic C4H::qsuB lines, the enzyme is targeted to the plastids via plastid-targeting signal peptide (SCHL), reduces lignin content and improves biomass saccharification efficiency, reduction of lignin deposition. Compared to wild-type plants, lines expressing QsuB contain higher amount of protocatechuate, p-coumarate, p-coumaraldehyde and p-coumaryl alcohol, and lower amounts of coniferaldehyde, coniferyl alcohol, sinapaldehyde, and sinapyl alcohol. Metabolite analysis of C4H::qsuB lines, overview. Recombinant expression of YFP-tagged enzyme in plastids of transgenic Arabidopsis thaliana

Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3-dehydro-shikimate	Corynebacterium glutamicum	-	protocatechuate + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3-dehydro-shikimate	-	Corynebacterium glutamicum	protocatechuate + H2O	-	?

Subunits

Subunits	Comment	Organism
?	x * 70000, SDS-PAGE	Corynebacterium glutamicum

Synonyms

Synonyms	Comment	Organism
QsuB	-	Corynebacterium glutamicum

General Information

General Information	Comment	Organism
metabolism	lignin biosynthetic pathway and heterologous expression of bacterial 3-dehydroshikimate dehydratase	Corynebacterium glutamicum
physiological function	the enzyme converts 3-dehydroshikimate, an intermediate of the shikimate pathway, into protocatechuate	Corynebacterium glutamicum