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Literature summary for 4.2.1.115 extracted from

  • Schoenhofen, I.C.; McNally, D.J.; Brisson, J.; Logan, S.M.
    Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction (2006), Glycobiology, 16, 8C-14C.
    View publication on PubMed
Search for more literature for 4.2.1.115

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetylglucosamine Helicobacter pylori production of a precursor of pseudaminic acid, i.e. 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid, required for flagellin glycosylation in Helicobacter pylori, analysis of all reaction steps in the pathway and related enzymes, overview UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + H2O
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 ?

Organism

Organism UniProt Comment Textmining
Helicobacter pylori
-
 gene pseB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetylglucosamine
-
 Helicobacter pylori UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + H2O
-
 ?
UDP-N-acetylglucosamine production of a precursor of pseudaminic acid, i.e. 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid, required for flagellin glycosylation in Helicobacter pylori, analysis of all reaction steps in the pathway and related enzymes, overview Helicobacter pylori UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + H2O
-
 ?

Synonyms

Synonyms Comment Organism
NAD(P)+-dependent dehydratase/epimerase
-
 Helicobacter pylori
PseB
-
 Helicobacter pylori

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Helicobacter pylori

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3
-
 assay at Helicobacter pylori