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Literature summary for 4.2.1.11 extracted from
- Molecular and biochemical characterization of Taenia solium alpha-enolase (2018), Vet. Parasitol., 254, 36-42 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CaCl2 | 5 mM, about 10% residual activity | Taenia solium |  |
| KCl | activating at 50-200 mM, inhibitory above | Taenia solium | |
| MgCl2 | inhibitory above 50 mM | Taenia solium | |
| NaCl | inhibitory above 50 mM | Taenia solium | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.1 | - |
2-phospho-D-glycerate | pH not specified in the publication, temperature not specified in the publication | Taenia solium | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| KCl | activating at 50-200 mM, inhibitory above | Taenia solium | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Taenia solium | V5T827 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adult | expression is 2.38fold higher in the adult worms than in the cysticerci | Taenia solium | - |
| cysticercus | expression is 2.38fold higher in the adult worms than in the cysticerci | Taenia solium | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 60.72 | - |
pH not specified in the publication, temperature not specified in the publication | Taenia solium |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-phospho-D-glycerate | - |
Taenia solium | phosphoenolpyruvate + H2O | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.5 | - |
Taenia solium |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | enzyme can bind to human plasminogen and generate plasmin, activated by a tissue-type plasminogen activator. 6-Aminocaproic acid inhibits the binding of plasminogen to Eno | Taenia solium |
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