Literature summary for 4.2.1.11 extracted from

Zhang, S.; Guo, A.; Zhu, X.; You, Y.; Hou, J.; Wang, Q.; Luo, X.; Cai, X.
Identification and functional characterization of alpha-enolase from Taenia pisiformis metacestode (2015), Acta Trop., 144, 31-40 .

Search for more literature for 4.2.1.11

Application

Application	Comment	Organism
medicine	vaccine with the enzyme can produce a 36.4% protection rate in vaccinated rabbits against experimental challenges from Taenia pisiformis eggs	Taenia pisiformis

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.6	-	phosphoenolpyruvate	22°C, pH not specified in the publication	Taenia pisiformis
0.77	-	2-phospho-D-glycerate	22°C, pH not specified in the publication	Taenia pisiformis

Organism

Organism	UniProt	Comment	Textmining
Taenia pisiformis	T1WGD6	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	sequence contains two putative N-linked glycosylation sites at positions 17-NPT-19 and 177-NFT-179	Taenia pisiformis

Source Tissue

Source Tissue	Comment	Organism	Textmining
metacestode	bladder wall of the metacestode	Taenia pisiformis	-
additional information	enzyme is distributed in the periphery of calcareous corpuscles	Taenia pisiformis	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
11.29	-	substrate phosphoenolpyruvate, 22°C, pH not specified in the publication	Taenia pisiformis
30.71	-	substrate 2-phospho-D-glycerate, 22°C, pH not specified in the publication	Taenia pisiformis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-phospho-D-glycerate	-	Taenia pisiformis	phosphoenolpyruvate + H2O	-	r
phosphoenolpyruvate + H2O	-	Taenia pisiformis	2-phospho-D-glycerate	-	r

Subunits

Subunits	Comment	Organism
?	x * 47000, calculated from sequence, x * 66000, SDS-PAGE	Taenia pisiformis

pI Value

Organism	Comment	pI Value Maximum	pI Value
Taenia pisiformis	calculated from sequence	-	6.8

General Information

General Information	Comment	Organism
physiological function	enzyme can bind to gen, binding is competitively inhibited by epsilon-aminocaproic acid. Plasminogen bound to Eno can be converted into active plasmin using host-derived activators	Taenia pisiformis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)