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Literature summary for 4.2.1.108 extracted from

  • Louis, P.; Galinski, E.A.
    Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli (1997), Microbiology, 143, 1141-1149.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information high salinity/osmolarity of the medium induces enzyme expression Marinococcus halophilus

Application

Application Comment Organism
biotechnology inducible recombinant enzyme expression in Escherichia coli confers the capability to grow on high concentration of osmolytes by increasing the osmotolerance via L-ectoine production Marinococcus halophilus

Cloned(Commentary)

Cloned (Comment) Organism
gene ectC, DNA and amino acid sequence determination and analysis, genetic mapping and organization, functional expression in Escherichia coli, the recombinant enzyme expression is osmoregulated in response to medium salinity in Escherichia coli Marinococcus halophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-N-acetyl-L-2,4-diaminobutanoate Marinococcus halophilus final step in L-ectoine biosynthesis, pathway overview L-ectoine + H2O
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 ?
additional information Marinococcus halophilus the enzyme is osmoregulated in response to medium salinity allowing the organism to live in environments with high concentration of osmolytes ?
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 ?

Organism

Organism UniProt Comment Textmining
Marinococcus halophilus O06061 gene ectC
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, pathway overview Marinococcus halophilus L-ectoine + H2O
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 ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Marinococcus halophilus L-ectoine + H2O
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 ?
additional information the enzyme is osmoregulated in response to medium salinity allowing the organism to live in environments with high concentration of osmolytes Marinococcus halophilus ?
-
 ?