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Literature summary for 4.2.1.108 extracted from

  • Kuhlmann, A.U.; Bremer, E.
    Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp. (2002), Appl. Environ. Microbiol., 68, 772-783.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.108

Activating Compound

Activating Compound Comment Organism Structure
additional information high osmolarity induces the enzyme expression, requirements Virgibacillus pantothenticus
additional information high osmolarity induces the enzyme expression, requirements Alkalihalobacillus alcalophilus
additional information high osmolarity induces the enzyme expression, requirements Sporosarcina psychrophila
additional information high osmolarity induces the enzyme expression, requirements Sporosarcina pasteurii
additional information high osmolarity induces the enzyme expression, requirements Virgibacillus salexigens
additional information high osmolarity induces the enzyme expression, requirements Chromohalobacter salexigens

Cloned(Commentary)

Cloned (Comment) Organism
gene ectC encoded in the ectABC gene cluster, functional expression in Escherichia coli Chromohalobacter salexigens
gene ectC, encoded in the ectABC gene cluster, sequence determination and analysis, phylogenetic analysis, DNA sequence comparison, expression in Escherichia coli Sporosarcina pasteurii

Metals/Ions

Metals/Ions Comment Organism Structure
NaCl required for activity Sporosarcina pasteurii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-N-acetyl-L-2,4-diaminobutanoate Virgibacillus pantothenticus final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate Alkalihalobacillus alcalophilus final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate Sporosarcina psychrophila final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate Sporosarcina pasteurii final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate Virgibacillus salexigens final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate Chromohalobacter salexigens final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant L-ectoine + H2O
-
 ?
additional information Virgibacillus pantothenticus phylogenetic analysis ?
-
 ?
additional information Alkalihalobacillus alcalophilus phylogenetic analysis ?
-
 ?
additional information Sporosarcina psychrophila phylogenetic analysis ?
-
 ?
additional information Sporosarcina pasteurii phylogenetic analysis ?
-
 ?
additional information Virgibacillus salexigens phylogenetic analysis ?
-
 ?
additional information Chromohalobacter salexigens phylogenetic analysis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Alkalihalobacillus alcalophilus
-
 strain DSM 485
-
Chromohalobacter salexigens Q9ZEU6 formerly Halomonas elongata, strain DSM 3043, gene ectC encoded in the ectABC gene cluster
-
no activity in Aneurinibacillus aneurinilyticus
-
 formerly Bacillus aneurinilyticus
-
no activity in Aneurinibacillus aneurinilyticus DSM 5562
-
 formerly Bacillus aneurinilyticus
-
no activity in Bacillus cereus
-
 strain DSM31
-
no activity in Bacillus cereus DSM 31
-
 strain DSM31
-
no activity in Bacillus circulans
-
 strain DSM 9
-
no activity in Bacillus licheniformis
-
 strain DSM 13
-
no activity in Bacillus megaterium
-
 strain DSM 32
-
no activity in Bacillus subtilis
-
-
-
no activity in Bacillus subtilis JH642
-
-
-
no activity in Bacillus thuringiensis
-
 strain DSM 2046
-
no activity in Paenibacillus polymyxa
-
 strain DSM 36
-
Sporosarcina pasteurii Q9AP33 strain DSM 33, gene ectC encoded in the ectABC gene cluster
-
Sporosarcina psychrophila
-
 formerly Bacillus psychrophilus, strain DSM 3
-
Virgibacillus pantothenticus
-
 formerl Bacillus pantothenticus, strain DSM 26
-
Virgibacillus salexigens
-
 formerly Bacillus salexigens, strain DSM 11438
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Virgibacillus pantothenticus L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Alkalihalobacillus alcalophilus L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Sporosarcina psychrophila L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Sporosarcina pasteurii L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Virgibacillus salexigens L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate final step in L-ectoine biosynthesis, L-ectoine acts as an osmoprotectant Chromohalobacter salexigens L-ectoine + H2O
-
 ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Sporosarcina psychrophila L-ectoine + H2O NMR identification ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Sporosarcina pasteurii L-ectoine + H2O NMR identification ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Virgibacillus pantothenticus L-ectoine + H2O NMR product identification ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Alkalihalobacillus alcalophilus L-ectoine + H2O NMR product identification ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Virgibacillus salexigens L-ectoine + H2O NMR product identification ?
4-N-acetyl-L-2,4-diaminobutanoate i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid Chromohalobacter salexigens L-ectoine + H2O NMR product identification ?
additional information phylogenetic analysis Virgibacillus pantothenticus ?
-
 ?
additional information phylogenetic analysis Alkalihalobacillus alcalophilus ?
-
 ?
additional information phylogenetic analysis Sporosarcina psychrophila ?
-
 ?
additional information phylogenetic analysis Sporosarcina pasteurii ?
-
 ?
additional information phylogenetic analysis Virgibacillus salexigens ?
-
 ?
additional information phylogenetic analysis Chromohalobacter salexigens ?
-
 ?