Literature summary for 4.2.1.10 extracted from

Light, S.H.; Antanasijevic, A.; Krishna, S.N.; Caffrey, M.; Anderson, W.F.; Lavie, A.
Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of Schiff base formation (2014), Biochemistry, 53, 872-880.

Search for more literature for 4.2.1.10

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Salmonella enterica

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with quinate and shikimate, sitting drop vapor diffusion method, using 0.01 M nickel chloride, 0.1 M Tris (pH 8.5), and 20% poly(ethylene glycol) monomethyl ether 2000	Salmonella enterica

Protein Variants

Protein Variants	Comment	Organism
K170M	the mutant shows enhanced affinity towards quinate and shikimate	Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3-dehydroquinate	Salmonella enterica	-	3-dehydroshikimate + H2O	-	r

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica	P58687	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA column chromatography	Salmonella enterica

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3-dehydroquinate	-	Salmonella enterica	3-dehydroshikimate + H2O	-	r

Synonyms

Synonyms	Comment	Organism
DHQD	-	Salmonella enterica
type I dehydroquinate dehydratase	-	Salmonella enterica

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Release 2023.1 (January 2023)