Crystallization (Comment) | Organism |
---|---|
sitting drop vapor diffusion method, using 26% (w/v) polyethyleneglycol 4000 and 0.1 M 2-(N-morpholino)ethanesulfonic acid sodium hydroxide, pH 5.0 | Helicobacter pylori |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(1R,4R,5R)-1,4,5-trihydroxy-3-(3-phenoxyphenyl)cyclohex-2-ene-1-carboxylic acid | competitive inhibitor | Helicobacter pylori | |
(1R,4R,5R)-1,4,5-trihydroxy-3-(thiophen-2-yl)cyclohex-2-ene-1-carboxylic acid | competitive inhibitor | Helicobacter pylori | |
(1R,4S,5R)-1,3,4,5-tetrahydroxycyclohex-2-ene-1-carboxylate | - |
Helicobacter pylori | |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(5-methylbenzo[b]-thiophen-2-yl)methoxycyclohex-2-en-1-carboxylate | - |
Helicobacter pylori | |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(benzo[b]thiophen-2-yl)methoxycyclohex-2-en-1-carboxylate | - |
Helicobacter pylori | |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(thien-2-yl)methoxycyclohex-2-en-1-carboxylate | - |
Helicobacter pylori | |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-[(benzo[b]thiophen-5-yl)methoxy]cyclohex-2-en-1-carboxylate | - |
Helicobacter pylori |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helicobacter pylori | Q48255 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-dehydroquinate | - |
Helicobacter pylori | 3-dehydroshikimate + H2O | - |
r |
Synonyms | Comment | Organism |
---|---|---|
DHQ2 | - |
Helicobacter pylori |
Type II dehydroquinase | - |
Helicobacter pylori |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00013 | - |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(5-methylbenzo[b]-thiophen-2-yl)methoxycyclohex-2-en-1-carboxylate | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori | |
0.000132 | - |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(benzo[b]thiophen-2-yl)methoxycyclohex-2-en-1-carboxylate | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori | |
0.000166 | - |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-[(benzo[b]thiophen-5-yl)methoxy]cyclohex-2-en-1-carboxylate | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori | |
0.00049 | - |
(1R,4R,5R)-1,4,5-trihydroxy-3-(3-phenoxyphenyl)cyclohex-2-ene-1-carboxylic acid | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori | |
0.00059 | - |
(1R,4R,5R)-1,4,5-trihydroxy-3-(thiophen-2-yl)cyclohex-2-ene-1-carboxylic acid | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori | |
0.00092 | - |
sodium (1R,4S,5R)-1,4,5-trihydroxy-3-(thien-2-yl)methoxycyclohex-2-en-1-carboxylate | in 50 mM Tris-HCl, pH 7, at 25°C | Helicobacter pylori |