Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Mycobacterium tuberculosis | |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Streptomyces coelicolor | |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Mycobacterium tuberculosis | |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | inhibitor is selective for the type II dehydroquinase over the type I dehydroquinase | Streptomyces coelicolor |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WPX7 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WPX7 | - |
- |
Salmonella enterica subsp. enterica serovar Typhi | - |
- |
- |
Streptomyces coelicolor | P15474 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Type I dehydroquinase | - |
Salmonella enterica subsp. enterica serovar Typhi |
Type II dehydroquinase | - |
Streptomyces coelicolor |
Type II dehydroquinase | - |
Mycobacterium tuberculosis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
0.015 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Streptomyces coelicolor | |
0.7 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Streptomyces coelicolor | |
0.7 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
1.5 | - |
(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
8 | - |
(1R,4S,5R)-3,3-difluoro-1,4,5-trihydroxycyclohexane-1-carboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi |