Literature summary for 4.2.1.10 extracted from

White, P.J.; Young, J.; Hunter, I.S.; Nimmo, H.G.; Coggins, J.R.
The purification and characterization of 3-dehydroquinase from Streptomyces coelicolor (1990), Biochem. J., 265, 735-738.

Search for more literature for 4.2.1.10

Inhibitors

Inhibitors	Comment	Organism	Structure
Cl-	no significant effect	Streptomyces coelicolor

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.6	-	3-dehydroquinate	-	Streptomyces coelicolor

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
16000	-	12 * 16000, SDS-PAGE	Streptomyces coelicolor
209000	-	gel filtration	Streptomyces coelicolor

Organism

Organism	UniProt	Comment	Textmining
Streptomyces coelicolor	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Streptomyces coelicolor

Reaction

Reaction	Comment	Organism	Reaction ID
3-dehydroquinate = 3-dehydroshikimate + H2O	the first step of the reaction involves the formation of an imine intermediate between the oxo group of the 3-dehydroquinate and the enzyme	Streptomyces coelicolor	a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
183.2	-	-	Streptomyces coelicolor

Storage Stability

Storage Stability	Organism
stable	Streptomyces coelicolor

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3-dehydroquinate	-	Streptomyces coelicolor	3-dehydroshikimate + H2O	-	?

Subunits

Subunits	Comment	Organism
dodecamer	12 * 16000, SDS-PAGE	Streptomyces coelicolor

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8	-	-	Streptomyces coelicolor

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Release 2023.1 (January 2023)