Literature summary for 4.2.1.1 extracted from

Moya, A.; Tambutte, S.; Bertucci, A.; Tambutte, E.; Lotto, S.; Vullo, D.; Supuran, C.T.; Allemand, D.; Zoccola, D.
Carbonic anhydrase in the scleractinian coral Stylophora pistillata: characterization, localization, and role in biomineralization (2008), J. Biol. Chem., 283, 25475-25484.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	the carbonic anhydrase gene is expressed 2fold more during the dark than the light	Stylophora pistillata

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli and in HEK-293 cells	Stylophora pistillata

Inhibitors

Inhibitors	Comment	Organism	Structure
acetazolamide	highly inhibited by acetazolamide, i.e. 5-acetamido-1,3,4-thiadiazole-2-sulfonamide	Stylophora pistillata

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
36600	-	calculated from amino acid sequence	Stylophora pistillata

Organism

Organism	UniProt	Comment	Textmining
Stylophora pistillata	B5SU02	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CO2 + H2O	-	Stylophora pistillata	H2CO3	-	r

Synonyms

Synonyms	Comment	Organism
carbonic anhydrase	-	Stylophora pistillata

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
310000	-	CO2	at 20°C and pH 7.5 in 10 mM HEPES buffer	Stylophora pistillata

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000016	-	acetazolamide	at 20°C and pH 7.5 in 10 mM HEPES buffer	Stylophora pistillata

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Release 2023.1 (January 2023)