Any feedback?
Literature summary for 4.2.1.1 extracted from
- Carbonic anhydrase inhibitors: Synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carbxamido moieties (2001), J. Enzyme Inhib., 16, 113-123.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| CA I and CA II cDNA expressed in Escherichia coli BL21 (DE3) | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-[cis-5-norbornene-endo-2,3-dicarboximidoethyl]-benzenesulfonamide | - |
Bos taurus |  |
| 4-[cis-5-norbornene-endo-2,3-dicarboximidomethyl]-benzenesulfonamide | - |
Bos taurus | |
| 4-[cis-5-norbornene-endo-2,3-dicarboximido]-benzenesulfonamide | - |
Bos taurus | |
| 4-[cis-5-norbornene-endo-3-carboxy-2-carboxamidoethyl]-benzenesulfonamide | - |
Bos taurus | |
| 4-[cis-5-norbornene-endo-3-carboxy-2-carboxamidomethyl]-benzenesulfonamide | - |
Bos taurus | |
| 4-[cis-5-norbornene-endo-3-carboxy-2-carboxamido]-benzenesulfonamide | - |
Bos taurus | |
| 5-[cis-5-norbornene-endo-2,3-dicarboximido]-1,3,4-thiadiazole-2-sulfonamide | - |
Bos taurus | |
| 5-[cis-5-norbornene-endo-3-carboxy-2-carboxamido]-1,3,4-thiadiazole-2-sulfonamide | - |
Bos taurus | |
| brinzolamide | - |
Bos taurus | |
| dorzolamide | - |
Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Bos taurus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2CO3 | Bos taurus | - |
CO2 + H2O | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl acetate + H2O | - |
Bos taurus | 4-nitrophenol + acetate | - |
r | |
| H2CO3 | - |
Bos taurus | CO2 + H2O | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| bCA IV | - |
Bos taurus |
| CA IV | - |
Bos taurus |
| carbonic anhydrase IV | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
