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Literature summary for 4.2.1.1 extracted from

  • Tu, C.; Rowlett, R.S.; Tripp, B.C.; Ferry, J.G.; Silverman, D.N.
    Chemical rescue of proton transfer in catalysis by carbonic anhydrases in the beta- and gamma-class (2002), Biochemistry, 41, 15429-15435.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
E84A proton shuttle replaced with a residue that does not transfer protons Methanosarcina thermophila
H216N proton shuttle replaced with a residue that does not transfer protons Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
Arabidopsis thaliana
Zn2+
-
Methanosarcina thermophila

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
H2CO3 Arabidopsis thaliana
-
CO2 + H2O
-
r
H2CO3 Methanosarcina thermophila
-
CO2 + H2O
-
r

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Methanosarcina thermophila
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Arabidopsis thaliana
-
Methanosarcina thermophila

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2CO3
-
Arabidopsis thaliana CO2 + H2O
-
r
H2CO3
-
Methanosarcina thermophila CO2 + H2O
-
r

Synonyms

Synonyms Comment Organism
carbonic anhydrase
-
Arabidopsis thaliana
carbonic anhydrase
-
Methanosarcina thermophila
E84A MTCA
-
Methanosarcina thermophila
H216N ATCA
-
Arabidopsis thaliana