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Literature summary for 4.2.1.1 extracted from

  • Mahieu, I.; Carter, N.; Hollande, E
    Characterization of a human ductal pancreatic Capan-1 clone (IMEH): carbonic anhydrases II and IV (CA II and CA IV) expression and targetting (1995), Biochem. Soc. Trans., 23, 309S.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane carbonic anhydrase IV is detected in the apical membrane of polarized cells Homo sapiens 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens carbonic anhydrase IV is possibly responsible for HCO3- secretion, the cytoplasmic form of carbonic anhydrase II is believed to play a role in pH regulation near apical ionic channels of the near apical carbonic anhydrase IV ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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carbonic anhydrase II
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Homo sapiens
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carbonic anhydrase IV
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Source Tissue

Source Tissue Comment Organism Textmining
liver Caplan-1 cell line, which is derived from a liver metastasis of pancreatic adenocarcinoma Homo sapiens
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pancreatic adenocarcinoma cell line Caplan-1 cell line, which is derived from a liver metastasis of pancreatic adenocarcinoma Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
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Homo sapiens H2CO3
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?
additional information carbonic anhydrase IV is possibly responsible for HCO3- secretion, the cytoplasmic form of carbonic anhydrase II is believed to play a role in pH regulation near apical ionic channels of the near apical carbonic anhydrase IV Homo sapiens ?
-
?