Literature summary for 4.1.99.25 extracted from

Chang, W.; Sanyal, D.; Huang, J.; Ittiamornkul, K.; Zhu, Q.; Liu, X.
In vitro stepwise reconstitution of amino acid derived vinyl isocyanide biosynthesis detection of an elusive intermediate (2017), Org. Lett., 19, 1208-1211 .

Search for more literature for 4.1.99.25

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-tryptophan + D-ribulose 5-phosphate	Xenorhabdus nematophila	the enzyme is involved in the biosynthetic pathways for vinyl isocyanides	(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Xenorhabdus nematophila	D3V9Q4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-tryptophan + D-ribulose 5-phosphate	the enzyme is involved in the biosynthetic pathways for vinyl isocyanides	Xenorhabdus nematophila	(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O	-	?
L-tryptophan + D-ribulose 5-phosphate	(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate i.e. L-tryptophan isonitrile, hydroxyacetone i.e. 1-hydroxypropan-2-one	Xenorhabdus nematophila	(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O	-	?

Synonyms

Synonyms	Comment	Organism
isnA	-	Xenorhabdus nematophila

General Information

General Information	Comment	Organism
metabolism	the enzyme is involved in the biosynthetic pathways for vinyl isocyanides	Xenorhabdus nematophila

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Release 2023.1 (January 2023)