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Literature summary for 4.1.99.16 extracted from

  • Schifrin, A.; Khatri, Y.; Kirsch, P.; Thiel, V.; Schulz, S.; Bernhardt, R.
    A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56 (2016), Org. Biomol. Chem., 14, 3385-3393 .
    View publication on PubMed
Search for more literature for 4.1.99.16

Cloned(Commentary)

Cloned (Comment) Organism
gene sce1440, recombinant expression in Escherichia coli Sorangium cellulosum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O Sorangium cellulosum
-
 (-)-geosmin + acetone
-
 ?
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O Sorangium cellulosum Soce56
-
 (-)-geosmin + acetone
-
 ?

Organism

Organism UniProt Comment Textmining
Sorangium cellulosum A9F845
-
-
Sorangium cellulosum Soce56 A9F845
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O
-
 Sorangium cellulosum (-)-geosmin + acetone
-
 ?
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O
-
 Sorangium cellulosum Soce56 (-)-geosmin + acetone
-
 ?
additional information the geosmin synthase sce1440 from Sorangium cellulosum strain Soce56 is very substrate-specific Sorangium cellulosum ?
-
 ?
additional information the geosmin synthase sce1440 from Sorangium cellulosum strain Soce56 is very substrate-specific Sorangium cellulosum Soce56 ?
-
 ?

Synonyms

Synonyms Comment Organism
sce1440
-
 Sorangium cellulosum

General Information

General Information Comment Organism
evolution identification of Sesquiterpene synthase orthologues of sce1440 in the genomes of myxobacterial strains, overview Sorangium cellulosum
metabolism the enzyme is one of only three type I terpene synthases (TSs, sce1440, sce6369, sce8552) and one type II TS (sce4636), responsible for the production of at least 17 sesquiterpenes in Sorangium cellulosum Sorangium cellulosum