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Literature summary for 4.1.3.4 extracted from

  • Leung, A.A.; Chan, A.K.; Ezekowitz, J.A.; Leung, A.K.
    A case of dilated cardiomyopathy associated with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) lyase deficiency (2009), Case Report Med., 2009, 183125.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.3.4

Application

Application Comment Organism
medicine dilated cardiomyopathy is associated with HMG CoA lyase deficiency Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-3-Hydroxy-3-methylglutaryl-CoA Homo sapiens
-
 Acetyl-CoA + acetoacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-Hydroxy-3-methylglutaryl-CoA
-
 Homo sapiens Acetyl-CoA + acetoacetate
-
 ?

Synonyms

Synonyms Comment Organism
3-hydroxy-3-methylglutaryl-coenzyme A lyase
-
 Homo sapiens
HMG CoA lyase
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency is an inborn error of metabolism characterized by impairment of ketogenesis and leucine catabolism resulting in an organic acidopathy Homo sapiens