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Literature summary for 4.1.3.3 extracted from

  • Mahmoudian, M.; Noble, D.; Drake, C.S.; Middleton, R.F.; Montgomery, D.S.; Piercey, J.E.; Ramlakhan, D.; Todd, M.; Dawson, M.J.
    An efficient process for production of N-acetylneuraminic acid using N-acetylneuramic acid aldolase (1997), Enzyme Microb. Technol., 45, 393-400.
No PubMed abstract available

Application

Application Comment Organism
synthesis production of N-acetyl-D-neuraminic acid, which is the major representative of amino sugars. The synthesis of N-acetyl-D-neuraminic acid is of interest in studies towards inhibitors of neuraminidase, hemagglutinin and selectin-mediated leucocyte adhesion Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-mannosamine + pyruvic acid
-
Escherichia coli N-acetyl-D-neuraminic acid
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
-
Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Escherichia coli