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Literature summary for 4.1.3.3 extracted from
- Studies on N-acetylneuraminic acid aldolase (1971), Biochem. J., 125, 275-285.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ag+ | - |
Clostridium perfringens |  |
| Bromopyruvate | 50% residual activity after incubation for 4.2 min with 1 mM bromopyruvate at pH 7.2, 37°C | Clostridium perfringens | |
| Hg2+ | - |
Clostridium perfringens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 3.3 | - |
N-acetylneuraminic acid | - |
Clostridium perfringens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no requirement | Clostridium perfringens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 250000 | - |
gel filtration | Clostridium perfringens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium perfringens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Clostridium perfringens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-Acetylneuraminic acid | - |
Clostridium perfringens | N-Acetyl-D-mannosamine + pyruvate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
enzyme assay at | Clostridium perfringens |
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Release 2023.1 (January 2023)
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