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Literature summary for 4.1.3.27 extracted from

  • Zhang, X.; Brotherton, J.; Widholm, J.
    Co-expression of the tobacco anthranilate synthase beta subunit with its feedback-insensitive alpha subunit as a selectable marker that also markedly increases the free tryptophan content (2015), In Vitro Cell. Dev. Biol. Plant, 51, 564-570 .
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Nicotiana tabacum

Inhibitors

Inhibitors Comment Organism Structure
7-methyltryptophan
-
Nicotiana tabacum
alpha-Methyltryptophan
-
Nicotiana tabacum
additional information subunit ASA2 is insensitive to tryptophan feedback inhibition Nicotiana tabacum
tryptophan complete inhibition at 0.02 mM Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
chorismate + L-glutamine Nicotiana tabacum
-
anthranilate + pyruvate + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
cultivar Xanthi
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chorismate + L-glutamine
-
Nicotiana tabacum anthranilate + pyruvate + L-glutamate
-
?

Subunits

Subunits Comment Organism
heterotetramer 2 * ? + 2 * 32000, SDS-PAGE Nicotiana tabacum

Synonyms

Synonyms Comment Organism
ASA2 alpha subunit Nicotiana tabacum
ASB beta subunit Nicotiana tabacum