Literature summary for 4.1.3.27 extracted from

Barone, P.; Widholm, J.M.
Use of 4-methylindole or 7-methyl-DL-tryptophan in a transformant selection system based on the feedback-insensitive anthranilate synthase alpha-subunit of tobacco (ASA2) (2008), Plant Cell Rep., 27, 509-517.

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Inhibitors

Inhibitors	Comment	Organism	Structure
4-methylindole	inhibits at 0.3 mM	Nicotiana tabacum
5-Methyltryptophan	less effective inhibitor than 4-methylindole or 7-methyl-DL-tryptophan	Nicotiana tabacum
7-methyl-DL-tryptophan	inhibits at 0.3 mM	Nicotiana tabacum

Organism

Organism	UniProt	Comment	Textmining
Nicotiana tabacum	-	cultivar Xanthi	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Nicotiana tabacum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
chorismate + L-Gln	-	Nicotiana tabacum	anthranilate + pyruvate + L-glutamate	-	?

Synonyms

Synonyms	Comment	Organism
ASA2	anthranilate synthase alpha-subunit	Nicotiana tabacum

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Release 2023.1 (January 2023)