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Literature summary for 4.1.3.27 extracted from

  • Payne, R.J.; Bulloch, E.M.; Abell, A.D.; Abell, C.
    Design and synthesis of aromatic inhibitors of anthranilate synthase (2005), Org. Biomol. Chem., 3, 3629-3635.
    View publication on PubMed
Search for more literature for 4.1.3.27

Inhibitors

Inhibitors Comment Organism Structure
(R)-3-(1-carboxy-ethoxy)benzoic acid
-
 Serratia marcescens
(S)-3-(1-carboxy-ethoxy)benzoic acid
-
 Serratia marcescens
3-(1-carboxy-ethoxy)-4-hydroxymethyl benzoic acid
-
 Serratia marcescens
3-(1-carboxy-ethoxy)-4-mercaptomethyl benzoic acid
-
 Serratia marcescens
3-(1-carboxy-ethoxy)-4-methyl benzoic acid
-
 Serratia marcescens
3-(1-carboxyethoxy)-4-hydroxybenzoic acid
-
 Serratia marcescens
3-(1-carboxyethoxy)-4-methoxybenzoic acid
-
 Serratia marcescens
4-amino-3-(1-carboxyethoxy)benzoic acid
-
 Serratia marcescens
4-aminomethyl-3-(1-carboxy-ethoxy)benzoate
-
 Serratia marcescens
4-azidomethyl-3-(1-carboxy-ethoxy)benzoic acid
-
 Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chorismate + L-Gln
-
 Serratia marcescens anthranilate + pyruvate + L-glutamate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0019
-
 (S)-3-(1-carboxy-ethoxy)benzoic acid pH 7.0, 25°C Serratia marcescens
0.0029
-
 3-(1-carboxyethoxy)-4-hydroxybenzoic acid pH 7.0, 25°C Serratia marcescens
0.0036
-
 (R)-3-(1-carboxy-ethoxy)benzoic acid pH 7.0, 25°C Serratia marcescens
0.021
-
 3-(1-carboxy-ethoxy)-4-mercaptomethyl benzoic acid pH 7.0, 25°C Serratia marcescens
0.021
-
 4-azidomethyl-3-(1-carboxy-ethoxy)benzoic acid pH 7.0, 25°C Serratia marcescens
0.023
-
 4-aminomethyl-3-(1-carboxy-ethoxy)benzoate pH 7.0, 25°C Serratia marcescens
0.024
-
 3-(1-carboxy-ethoxy)-4-hydroxymethyl benzoic acid pH 7.0, 25°C Serratia marcescens
0.025
-
 3-(1-carboxyethoxy)-4-methoxybenzoic acid pH 7.0, 25°C Serratia marcescens
0.026
-
 3-(1-carboxy-ethoxy)-4-methyl benzoic acid pH 7.0, 25°C Serratia marcescens
0.043
-
 4-amino-3-(1-carboxyethoxy)benzoic acid pH 7.0, 25°C Serratia marcescens