Any feedback?
Literature summary for 4.1.3.16 extracted from
- Substrates of hydroxyketoglutarate aldolase (1984), Bioorg. Chem., 12, 229-234.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | use as synthetic tool for C-C bond formation considered | Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus | |
| 2.8 | - |
Pyruvic acid ethyl ester | - |
Rattus norvegicus |  |
| 3.2 | - |
pyruvic acid methyl ester | - |
Rattus norvegicus | |
| 5.1 | - |
Pyruvaldehyde | - |
Rattus norvegicus | |
| 7.4 | - |
3-(4-imidazole)pyruvate | - |
Rattus norvegicus | |
| 7.7 | - |
3-(4-hydroxyphenyl)pyruvate | - |
Rattus norvegicus | |
| 10 | - |
acetaldehyde | - |
Rattus norvegicus | |
| 25 | - |
pyruvate | - |
Rattus norvegicus | |
| 30 | - |
oxaloacetate | condensation with glyoxylate | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no requirement | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
| 0.8 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-(4-hydroxyphenyl)pyruvate + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
| 3-(4-imidazole)pyruvate + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
| acetaldehyde + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
| Glyoxylate + pyruvate | 3-substituted analogs | Rattus norvegicus | 4-Hydroxy-2-ketoglutarate | - |
? | |
| additional information | - |
Rattus norvegicus | ? | - |
? | |
| Oxaloacetate | - |
Rattus norvegicus | CO2 + pyruvate | - |
? | |
| pyruvaldehyde + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
| pyruvic acid ethyl ester + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
| pyruvic acid methyl ester + glyoxylate | - |
Rattus norvegicus | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
