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Literature summary for 4.1.3.1 extracted from

  • Oh, K.B.; Jeon, H.B.; Han, Y.R.; Lee, Y.J.; Park, J.; Lee, S.H.; Yang, D.; Kwon, M.; Shin, J.; Lee, H.S.
    Bromophenols as Candida albicans isocitrate lyase inhibitors (2010), Bioorg. Med. Chem. Lett., 20, 6644-6648.
    View publication on PubMed
Search for more literature for 4.1.3.1

Cloned(Commentary)

Cloned (Comment) Organism
-
 Candida albicans

Inhibitors

Inhibitors Comment Organism Structure
(2-bromo-4,5-dihydroxybenzyl)(2,3-dibromo-4,5-dihydroxybenzyl) ether
-
 Candida albicans
(2-bromo-4,5-dihydroxyphenyl)(3,4-dihydroxyphenyl) ether
-
 Candida albicans
(3-bromo-4,5-dihydroxyphenyl)(2,3-dibromo-4,5-dihydroxyphenyl)methanone
-
 Candida albicans
2,2',3-tribromo-4,4',5,5'-tetrahydroxybibenzyl
-
 Candida albicans
2,2'-dibromo-4,4',5,5'-tetrahydroxybibenzyl
-
 Candida albicans
3-nitropropionate
-
 Candida albicans
4,4'-(oxydimethanediyl)bis(5,6-dibromobenzene-1,2-diol)
-
 Candida albicans
4,4'-ethane-1,2-diyldibenzene-1,2-diol
-
 Candida albicans
4,4'-methanediylbis(5,6-dibromobenzene-1,2-diol)
-
 Candida albicans
4,4'-methanediylbis(5-bromobenzene-1,2-diol)
-
 Candida albicans
bis(2,3-dibromo-4,5-dihydroxyphenyl) ether
-
 Candida albicans
bis(2-bromo-4,5-dihydroxyphenyl) ether
-
 Candida albicans
bis(3,4-dihydroxyphenyl)methanone
-
 Candida albicans
bis(3-bromo-4,5-dihydroxyphenyl)methanone
-
 Candida albicans

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-
Candida albicans ATCC 10231
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Candida albicans

Synonyms

Synonyms Comment Organism
isocitrate lyase
-
 Candida albicans

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00265
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans (3-bromo-4,5-dihydroxyphenyl)(2,3-dibromo-4,5-dihydroxyphenyl)methanone
0.00889
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans bis(3-bromo-4,5-dihydroxyphenyl)methanone
0.01163
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans bis(2,3-dibromo-4,5-dihydroxyphenyl) ether
0.01477
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 2,2',3-tribromo-4,4',5,5'-tetrahydroxybibenzyl
0.01561
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans (2-bromo-4,5-dihydroxybenzyl)(2,3-dibromo-4,5-dihydroxybenzyl) ether
0.01844
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 4,4'-methanediylbis(5,6-dibromobenzene-1,2-diol)
0.02121
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 2,2'-dibromo-4,4',5,5'-tetrahydroxybibenzyl
0.02258
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans bis(3,4-dihydroxyphenyl)methanone
0.02806
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 4,4'-(oxydimethanediyl)bis(5,6-dibromobenzene-1,2-diol)
0.03088
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans bis(2-bromo-4,5-dihydroxyphenyl) ether
0.04615
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 4,4'-methanediylbis(5-bromobenzene-1,2-diol)
0.0507
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 3-nitropropionate
0.05847
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans 4,4'-ethane-1,2-diyldibenzene-1,2-diol
0.06819
-
 pH not specified in the publication, temperature not specified in the publication Candida albicans (2-bromo-4,5-dihydroxyphenyl)(3,4-dihydroxyphenyl) ether