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Literature summary for 4.1.2.9 extracted from

  • Okano, K.; Yoshida, S.; Yamada, R.; Tanaka, T.; Ogino, C.; Fukuda, H.; Kondo, A.
    Improved production of homo-D-lactic acid via xylose fermentation by introduction of xylose assimilation genes and redirection of the phosphoketolase pathway to the pentose phosphate pathway in L-Lactate dehydrogenase gene-deficient Lactobacillus plantarum (2009), Appl. Environ. Microbiol., 75, 7858-7861.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
industry the production of D-lactic acid as well as L-lactic acid is of significant importance for the practical application of polylactic acid, which is an important raw material for bioplastics that can be produced from biomass Lactiplantibacillus plantarum

Protein Variants

Protein Variants Comment Organism
additional information since Lactobacillus plantarum has two phosphoketolase genes, xpk1 and xpk2, a delta xpk2 mutant is structured from Lactobacillus plantarum delta ldhL1-xpk1::tkt/pCU-PXylAB. Disruption of xpk2 causes a slight decrease in cell growth and fermentation rates, complete abolition of enzymes that have phosphoketolase activity, combined with introduction of enzymes that function as a bridge to the pentose phosphate pathway, enables homo-lactic acid production by pentose sugar fermentation Lactiplantibacillus plantarum

Organism

Organism UniProt Comment Textmining
Lactiplantibacillus plantarum
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Lactiplantibacillus plantarum NCIMB 8826 delta ldhL1 -xpk1::tkt-delta xpk
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Synonyms

Synonyms Comment Organism
phosphoketolase
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Lactiplantibacillus plantarum