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Literature summary for 4.1.2.47 extracted from

  • Froehlich, R.F.G.; Zabelinskaja-Mackova, A.A.; Fechter, M.H.; Griengl, H.
    Novel access to chiral 1,1'-disubstituted ferrocene derivatives via double stereoselective cyanohydrin synthesis exploiting the hydroxynitrile lyase from Hevea brasiliensis (2003), Tetrahedron, 14, 355-362.
No PubMed abstract available
Search for more literature for 4.1.2.47

Application

Application Comment Organism
synthesis production of chiral ferrocene derivatives as ligands in asymmetric catalysis, to bioelectrochemistry and development of new pharmaceuticals against malaria Hevea brasiliensis

Organism

Organism UniProt Comment Textmining
Hevea brasiliensis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetone cyanhydrin
-
 Hevea brasiliensis HCN + acetone
-
 ?
HCN + 1,1'-diformylferrocene
-
 Hevea brasiliensis (R,R)-1,1-bis(cyanohydroxymethyl)ferrocene
-
 ?
HCN + ferrocene aldehyde
-
 Hevea brasiliensis ?
-
 ?
HCN + formylferrocene
-
 Hevea brasiliensis (R)-(cyanohydroxymethyl)ferrocene
-
 ?
additional information acetylferrocene and 1,1'-diacetylferrocene are not transformed with this enzyme Hevea brasiliensis ?
-
 ?

Synonyms

Synonyms Comment Organism
(S)-HbHNL
-
 Hevea brasiliensis
Hydroxynitrile lyase
-
 Hevea brasiliensis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.8
-
 conversion of formylferrocene Hevea brasiliensis

pH Stability

pH Stability pH Stability Maximum Comment Organism
4.8
-
 still stable at this value Hevea brasiliensis