Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.2.46 extracted from

  • Liu, S.
    Asymmetric synthesis of silicon containing (R)-ketone cyanhydrin catalyzed by (R)-hydroxynitrile lyase from peach seed meal (2011), J. Shenzhen Univ. Sci. Eng., 28, 54-59.
No PubMed abstract available
Search for more literature for 4.1.2.46

Application

Application Comment Organism
synthesis production of organosilicon compounds by enantioselective transcyanation. Under optimum conditions, both acetyltrimethylsilane conversion to (R)-2-trimethylsilyl-2-hydroxy-ethylcyanide and enantiomeric excess of the product are above 99%. the silicon atom in acetyltrimethylsilane has a great effect on the eaction and both the substrate conversion and the product enantiomeric excess are much higher than those in its carbon counterpart 3,3-dimethyl-2-butanone Prunus persica

Organism

Organism UniProt Comment Textmining
Prunus persica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
seed defatted seed meal Prunus persica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,3-dimethyl-2-butanone + acetone cyanohydrin
-
 Prunus persica 2-hydroxy-2,3,3-trimethylbutanenitrile + acetone
-
 ?
acetyltrimethylsilane + acetone cyanohydrin
-
 Prunus persica (R)-2-trimethylsilyl-2-hydroxy-ethylcyanide + acetone enantioselective transcyanation. Under optimum conditions, both acetyltrimethylsilane conversion to (R)-2-trimethylsilyl-2-hydroxy-ethylcyanide and enantiomeric excess of the product are above 99%. The silicon atom in acetyltrimethylsilane has a great effect on the eaction and both the substrate conversion and the product enantiomeric excess are much higher than those in its carbon counterpart 3,3-dimethyl-2-butanone ?