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Literature summary for 4.1.2.32 extracted from

  • Myers, P.A.; Zatman, L.J.
    The metabolism of trimethylamine N-oxide by Bacillus PM 6 (1971), Biochem. J., 121, 10P.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.2.32

Activating Compound

Activating Compound Comment Organism Structure
glutathione strongly stimulates Bacillus sp. (in: Bacteria)
L-ascorbate strongly stimutates Bacillus sp. (in: Bacteria)

Inhibitors

Inhibitors Comment Organism Structure
Proadifen hydrochloride i.e. SKF 525-A, , competitive Bacillus sp. (in: Bacteria)
trimethylamine non-competitive Bacillus sp. (in: Bacteria)

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.85
-
 Trimethylamine N-oxide
-
 Bacillus sp. (in: Bacteria)

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ strongly stimulates Bacillus sp. (in: Bacteria)

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000 47000 sedimentation equilibrium centrifugation Bacillus sp. (in: Bacteria)
50000
-
 gel filtration Bacillus sp. (in: Bacteria)

Organism

Organism UniProt Comment Textmining
Bacillus sp. (in: Bacteria)
-
 PM 6
-
Bacillus sp. (in: Bacteria) PM 6
-
 PM 6
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-Propoxyphene N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
(+)-Propoxyphene N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
Benzyldimethylamine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
Benzyldimethylamine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
Chlorpromazine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
Chlorpromazine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
Trimethylamine N-oxide anaerobic conditions Bacillus sp. (in: Bacteria) Dimethylamine + formaldehyde
-
 ?
Trimethylamine N-oxide anaerobic conditions Bacillus sp. (in: Bacteria) PM 6 Dimethylamine + formaldehyde
-
 ?

Subunits

Subunits Comment Organism
monomer 1* 37000, SDS-PAGE Bacillus sp. (in: Bacteria)

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Bacillus sp. (in: Bacteria)