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Literature summary for 4.1.2.27 extracted from

  • Oskouian, B.; Sooriyakumaran, P.; Borowsky, A.D.; Crans, A.; Dillard-Telm, L.; Tam, Y.Y.; Bandhuvula, P.; Saba, J.D.
    Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer (2006), Proc. Natl. Acad. Sci. USA, 103, 17384-17389.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.2.27

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell line
-
 Homo sapiens
-
colonic cancer cell
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-
intestine
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingosine 1-phosphate
-
 Mus musculus phosphoethanolamine + palmitaldehyde
-
 ?
sphingosine 1-phosphate
-
 Homo sapiens phosphoethanolamine + palmitaldehyde
-
 ?

Synonyms

Synonyms Comment Organism
sphingosine-1-phosphate lyase
-
 Mus musculus
sphingosine-1-phosphate lyase
-
 Homo sapiens
SPL
-
 Mus musculus
SPL
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Mus musculus
pyridoxal 5'-phosphate
-
 Homo sapiens