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Literature summary for 4.1.2.23 extracted from

  • Wong, C.H.; Sugai, T.; Shen, G.J.
    KDO aldolase (1999), U. S. 23pp. Cont. -in part of U. S. 5,585,261, , .
No PubMed abstract available
Search for more literature for 4.1.2.23

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2
-
 3-deoxy-D-manno-octulosonate
-
 Microbacterium barkeri

Organism

Organism UniProt Comment Textmining
Enterobacter cloacae
-
-
-
Escherichia coli
-
 strain 0111, strain B, strain K-12
-
Microbacterium barkeri
-
 KDO-37-2
-
Microbacterium barkeri KDO-37-2
-
 KDO-37-2
-
Salmonella enterica subsp. enterica serovar Adelaide
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Microbacterium barkeri

Reaction

Reaction Comment Organism Reaction ID
3-deoxy-D-manno-octulosonate = pyruvate + D-arabinose the enzyme may accept the open form of aldoses as acceptors in the aldol condensation Microbacterium barkeri
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-deoxy-D-manno-octulosonate
-
 Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + D-arabinose
-
 ?
3-deoxy-D-manno-octulosonate
-
 Escherichia coli pyruvate + D-arabinose
-
 ?
3-deoxy-D-manno-octulosonate
-
 Enterobacter cloacae pyruvate + D-arabinose
-
 ?
3-deoxy-D-manno-octulosonate
-
 Microbacterium barkeri pyruvate + D-arabinose
-
 ?
3-deoxy-D-manno-octulosonate
-
 Salmonella enterica subsp. enterica serovar Adelaide pyruvate + D-arabinose
-
 ?
3-deoxy-D-manno-octulosonate
-
 Microbacterium barkeri KDO-37-2 pyruvate + D-arabinose
-
 ?
pyruvate + 2-deoxy-2-fluoro-D-arabinose at 46% of the activity with D-arabinose Microbacterium barkeri 3,5-dideoxy-5-fluoro-alpha-D-manno-2-octulosonic acid
-
 ?
pyruvate + 2-deoxy-D-ribose at 71% of the activity with D-arabinose Microbacterium barkeri 3,5-dideoxy-alpha-D-manno-2-octulosonic acid
-
 ?
pyruvate + 2-deoxy-D-ribose at 71% of the activity with D-arabinose Microbacterium barkeri KDO-37-2 3,5-dideoxy-alpha-D-manno-2-octulosonic acid
-
 ?
pyruvate + 5-azido-2,5-dideoxy-D-ribose at 15% of the activity with D-arabinose Microbacterium barkeri ?
-
 ?
pyruvate + D-altrose at 25% of the activity with D-arabinose Microbacterium barkeri D-erythrose + D-glyceraldehyde
-
 ?
pyruvate + D-erythrose at 93% of the activity with D-arabinose Microbacterium barkeri ?
-
 ?
pyruvate + D-erythrose at 93% of the activity with D-arabinose Microbacterium barkeri KDO-37-2 ?
-
 ?
pyruvate + D-glyceraldehyde at 23% of the activity with D-arabinose Microbacterium barkeri 2-dehydro-3-deoxy-D-galactonate
-
 ?
pyruvate + D-lyxose at 35% of the activity with D-arabinose Microbacterium barkeri ?
-
 ?
pyruvate + D-ribose
-
 Enterobacter cloacae ?
-
 ?
pyruvate + D-ribose at 72% of the activity with D-arabinose Microbacterium barkeri ?
-
 ?
pyruvate + D-ribose at 72% of the activity with D-arabinose Microbacterium barkeri KDO-37-2 ?
-
 ?
pyruvate + D-threose at 128% of the activity with D-arabinose Microbacterium barkeri ?
-
 ?
pyruvate + D-threose at 128% of the activity with D-arabinose Microbacterium barkeri KDO-37-2 ?
-
 ?
pyruvate + L-glyceraldehyde at 36% of the activity with D-arabinose Microbacterium barkeri 2-keto-3-deoxy-L-gluconic acid
-
 ?