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Literature summary for 4.1.2.21 extracted from

  • Henderson, D.P.; Cotterill, I.C.; Shelton, M.C.; Toone, E.J.
    2-Keto-3-deoxy-6-phosphogalactonate aldolase as a catalyst for stereocontrolled carbon-carbon bond formation (1998), J. Org. Chem., 63, 906-907.
No PubMed abstract available
Search for more literature for 4.1.2.21

Application

Application Comment Organism
synthesis the enzyme can stereospecifically catalyze aldol addition with unnatural electrophilic substrates at rates practical for preparative scale organic synthesis Burkholderia cepacia

General Stability

General Stability Organism
stable during isolation and lyophilization Burkholderia cepacia

Organism

Organism UniProt Comment Textmining
Burkholderia cepacia
-
-
-
Burkholderia cepacia 249-27
-
-
-

Storage Stability

Storage Stability Organism
-78°C, stable for at least months Burkholderia cepacia

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-dehydro-3-deoxy-D-galactonate 6-phosphate
-
 Burkholderia cepacia pyruvate + D-glyceraldehyde 3-phosphate
-
 ?
2-dehydro-3-deoxy-D-galactonate 6-phosphate
-
 Burkholderia cepacia 249-27 pyruvate + D-glyceraldehyde 3-phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Burkholderia cepacia

pH Range

pH Minimum pH Maximum Comment Organism
6.5 9.5 more than 50% of maximal activity at pH 6.5 and at pH 9.5 Burkholderia cepacia