Literature summary for 4.1.2.17 extracted from

Samuel, J.; Luo, Y.; Morgan, P.M.; Strynadka, N.C.; Tanner, M.E.
Catalysis and binding in L-ribulose-5-phosphate 4-epimerase: a comparison with L-fuculose-1-phosphate aldolase (2001), Biochemistry, 40, 14772-14780.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
cocrystallized with phosphoglycolohydroxamate	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
D120N	mutant with reduced specific activity	Escherichia coli
D76E	mutant with reduced specific activity	Escherichia coli
E142Q	mutant with increased specific activity	Escherichia coli
H218N	mutant with reduced specific activity	Escherichia coli
H97N	mutant with reduced specific activity	Escherichia coli
K42M	mutant with reduced specific activity, can be inhibited by excess Zn2+	Escherichia coli
N28A	mutant with reduced specific activity	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.00055	-	H218N mutant	Escherichia coli
0.0011	-	D76E mutant	Escherichia coli
0.0012	-	D120N mutant	Escherichia coli
0.0013	-	K42M mutant	Escherichia coli
0.0061	-	N28A mutant	Escherichia coli
0.0063	-	H97N mutant	Escherichia coli
0.0085	-	wild-type	Escherichia coli
0.0122	-	E142Q mutant	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-fuculose 1-phosphate	-	Escherichia coli	glycerone phosphate + (S)-lactaldehyde	-	r

Synonyms

Synonyms	Comment	Organism
L-Fuc1P aldolase	-	Escherichia coli

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Release 2023.1 (January 2023)