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Literature summary for 4.1.2.13 extracted from

  • Sun, Z.; Shen, B.; Wu, H.; Zhou, X.; Wang, Q.; Xiao, J.; Zhang, Y.
    The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture (2015), Fish Shellfish Immunol., 46, 638-647 .
    View publication on PubMed
Search for more literature for 4.1.2.13

Application

Application Comment Organism
agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Edwardsiella tarda
agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio anguillarum
agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Aeromonas hydrophila
agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio campbellii
agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio alginolyticus
drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Edwardsiella tarda
drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio anguillarum
drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Aeromonas hydrophila
drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio campbellii
drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio alginolyticus
medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio harveyi
medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Aeromonas hydrophila
medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio alginolyticus
medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio anguillarum
medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Edwardsiella tarda

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Vibrio harveyi
expressed in Escherichia coli BL21(DE3) cells Aeromonas hydrophila
expressed in Escherichia coli BL21(DE3) cells Vibrio alginolyticus
expressed in Escherichia coli BL21(DE3) cells Vibrio anguillarum
expressed in Escherichia coli BL21(DE3) cells Edwardsiella tarda
expression in Escherichia coli Edwardsiella tarda
expression in Escherichia coli Vibrio anguillarum
expression in Escherichia coli Aeromonas hydrophila
expression in Escherichia coli Vibrio campbellii
expression in Escherichia coli Vibrio alginolyticus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Edwardsiella tarda
-
-
extracellular
-
 Vibrio anguillarum
-
-
extracellular
-
 Aeromonas hydrophila
-
-
extracellular
-
 Vibrio campbellii
-
-
extracellular
-
 Vibrio alginolyticus
-
-
membrane
-
 Edwardsiella tarda 16020
-
membrane
-
 Vibrio anguillarum 16020
-
membrane
-
 Aeromonas hydrophila 16020
-
membrane
-
 Vibrio campbellii 16020
-
membrane
-
 Vibrio alginolyticus 16020
-
periplasm
-
 Edwardsiella tarda
-
-
periplasm
-
 Vibrio anguillarum
-
-
periplasm
-
 Aeromonas hydrophila
-
-
periplasm
-
 Vibrio campbellii
-
-
periplasm
-
 Vibrio alginolyticus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-fructose 1,6-bisphosphate Vibrio harveyi
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Aeromonas hydrophila
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Vibrio alginolyticus
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Vibrio anguillarum
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Edwardsiella tarda
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Vibrio harveyi ATCC BAA-1116
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Vibrio anguillarum MVM425
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Edwardsiella tarda EIB202
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Vibrio alginolyticus 12G01
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate Aeromonas hydrophila ATCC7699
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Aeromonas hydrophila
-
-
-
Aeromonas hydrophila A0KGD4
-
-
Aeromonas hydrophila ATCC 7699 A0KGD4
-
-
Aeromonas hydrophila ATCC7699
-
-
-
Edwardsiella tarda
-
-
-
Edwardsiella tarda D0ZEE4
-
-
Edwardsiella tarda EIB202
-
-
-
Edwardsiella tarda EIB202 D0ZEE4
-
-
Vibrio alginolyticus
-
-
-
Vibrio alginolyticus A7MTQ6
-
-
Vibrio alginolyticus 12G01
-
-
-
Vibrio alginolyticus 12G01 A7MTQ6
-
-
Vibrio anguillarum
-
-
-
Vibrio anguillarum D0ZEE4
-
-
Vibrio anguillarum MVM425
-
-
-
Vibrio anguillarum MVM425 D0ZEE4
-
-
Vibrio campbellii A7MTQ6
-
-
Vibrio campbellii ATCC BAA-1116 A7MTQ6
-
-
Vibrio harveyi
-
-
-
Vibrio harveyi ATCC BAA-1116
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Edwardsiella tarda
-
 Vibrio anguillarum
-
 Aeromonas hydrophila
-
 Vibrio campbellii
-
 Vibrio alginolyticus
Ni-NTA column chromatography Vibrio harveyi
Ni-NTA column chromatography Aeromonas hydrophila
Ni-NTA column chromatography Vibrio alginolyticus
Ni-NTA column chromatography Vibrio anguillarum
Ni-NTA column chromatography Edwardsiella tarda

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate
-
 Vibrio harveyi glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Aeromonas hydrophila glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Vibrio alginolyticus glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Vibrio anguillarum glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Edwardsiella tarda glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Vibrio harveyi ATCC BAA-1116 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Vibrio anguillarum MVM425 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Edwardsiella tarda EIB202 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Vibrio alginolyticus 12G01 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
D-fructose 1,6-bisphosphate
-
 Aeromonas hydrophila ATCC7699 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
FBA
-
 Vibrio harveyi
FBA
-
 Aeromonas hydrophila
FBA
-
 Vibrio alginolyticus
FBA
-
 Vibrio anguillarum
FBA
-
 Edwardsiella tarda
FBA
-
 Vibrio campbellii
Fructose 1,6-bisphosphate aldolase
-
 Vibrio harveyi
Fructose 1,6-bisphosphate aldolase
-
 Aeromonas hydrophila
Fructose 1,6-bisphosphate aldolase
-
 Vibrio alginolyticus
Fructose 1,6-bisphosphate aldolase
-
 Vibrio anguillarum
Fructose 1,6-bisphosphate aldolase
-
 Edwardsiella tarda
Fructose 1,6-bisphosphate aldolase
-
 Vibrio campbellii

General Information

General Information Comment Organism
evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Edwardsiella tarda
evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio anguillarum
evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Aeromonas hydrophila
evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio campbellii
evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio alginolyticus
physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Edwardsiella tarda
physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio anguillarum
physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Aeromonas hydrophila
physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio campbellii
physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio alginolyticus