Crystallization (Comment) | Organism |
---|---|
- |
Helicobacter pylori |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-(3-hydroxypropyl)-glycolohydrazide-bisphosphate | fructose-1,6-bisphosphate analogue | Helicobacter pylori | |
N-(3-hydroxypropyl)-glycolohydrazide-bisphosphate | fructose-1,6-bisphosphate analogue | Mycobacterium tuberculosis | |
N-(3-hydroxypropyl)-glycolohydrazide-bisphosphate | fructose-1,6-bisphosphate analogue | Oryctolagus cuniculus | |
N-(3-hydroxypropyl)-glycolohydrazide-bisphosphate | fructose-1,6-bisphosphate analogue | Saccharomyces cerevisiae | |
N-(3-hydroxypropyl)-glycolohydroxamic acid bisphosphate | fructose-1,6-bisphosphate analogue, best results | Helicobacter pylori | |
N-(3-hydroxypropyl)-glycolohydroxamic acid bisphosphate | fructose-1,6-bisphosphate analogue, weakly active | Mycobacterium tuberculosis | |
N-(3-hydroxypropyl)-glycolohydroxamic acid bisphosphate | fructose-1,6-bisphosphate analogue, best results | Oryctolagus cuniculus | |
N-(3-hydroxypropyl)-glycolohydroxamic acid bisphosphate | fructose-1,6-bisphosphate analogue, best results | Saccharomyces cerevisiae | |
N-(3-hydroxypropyl)-phosphoglycolohydroxamic acid | fructose-1,6-bisphosphate analogue | Helicobacter pylori | |
N-(3-hydroxypropyl)-phosphoglycolohydroxamic acid | fructose-1,6-bisphosphate analogue | Mycobacterium tuberculosis | |
N-(3-hydroxypropyl)-phosphoglycolohydroxamic acid | fructose-1,6-bisphosphate analogue | Oryctolagus cuniculus | |
N-(3-hydroxypropyl)-phosphoglycolohydroxamic acid | fructose-1,6-bisphosphate analogue | Saccharomyces cerevisiae | |
phosphoglycoloamidoxime | dihydroxyacetone phosphate analogue | Helicobacter pylori | |
phosphoglycoloamidoxime | dihydroxyacetone phosphate analogue | Mycobacterium tuberculosis | |
phosphoglycoloamidoxime | dihydroxyacetone phosphate analogue | Oryctolagus cuniculus | |
phosphoglycoloamidoxime | dihydroxyacetone phosphate analogue | Saccharomyces cerevisiae | |
phosphoglycolohydrazide | dihydroxyacetone phosphate analogue | Helicobacter pylori | |
phosphoglycolohydrazide | dihydroxyacetone phosphate analogue | Mycobacterium tuberculosis | |
phosphoglycolohydrazide | dihydroxyacetone phosphate analogue | Oryctolagus cuniculus | |
phosphoglycolohydrazide | dihydroxyacetone phosphate analogue | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
D-fructose-1,6-bisphosphate | - |
Helicobacter pylori | |
0.055 | - |
D-fructose-1,6-bisphosphate | - |
Oryctolagus cuniculus | |
0.45 | - |
D-fructose-1,6-bisphosphate | - |
Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | - |
Mycobacterium tuberculosis | |
Co2+ | - |
Oryctolagus cuniculus | |
Co2+ | - |
Saccharomyces cerevisiae | |
Co2+ | - |
Helicobacter pylori | |
Zn2+ | - |
Mycobacterium tuberculosis | |
Zn2+ | - |
Oryctolagus cuniculus | |
Zn2+ | - |
Saccharomyces cerevisiae | |
Zn2+ | - |
Helicobacter pylori |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose-1,6-bisphosphate | Mycobacterium tuberculosis | - |
dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | Oryctolagus cuniculus | - |
dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | Saccharomyces cerevisiae | - |
dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | Helicobacter pylori | - |
dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | Mycobacterium tuberculosis H37Rv | - |
dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helicobacter pylori | P56109 | - |
- |
Mycobacterium tuberculosis | P9WQA3 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WQA3 | - |
- |
Oryctolagus cuniculus | P00883 | - |
- |
Saccharomyces cerevisiae | P14540 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose-1,6-bisphosphate | - |
Mycobacterium tuberculosis | dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | - |
Oryctolagus cuniculus | dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | - |
Saccharomyces cerevisiae | dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | - |
Helicobacter pylori | dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r | |
D-fructose-1,6-bisphosphate | - |
Mycobacterium tuberculosis H37Rv | dihydroxyacetone phosphate + glyceraldehyde-3-phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
class I fructose bisphosphate aldolase | - |
Oryctolagus cuniculus |
class II fructose bisphosphate aldolase | - |
Mycobacterium tuberculosis |
class II fructose bisphosphate aldolase | - |
Saccharomyces cerevisiae |
class II fructose bisphosphate aldolase | - |
Helicobacter pylori |
FBA | - |
Mycobacterium tuberculosis |
FBA | - |
Oryctolagus cuniculus |
FBA | - |
Saccharomyces cerevisiae |
FBA | - |
Helicobacter pylori |