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Literature summary for 4.1.2.13 extracted from

  • Blonski, C.; de Moissac, D.; Perie, J.; Sygusch, J.
    Inhibition of rabbit muscle aldolase by phosphorylated aromatic compounds (1997), Biochem. J., 323, 71-77.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.2.13

Protein Variants

Protein Variants Comment Organism
E187Q K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate Oryctolagus cuniculus
K107M K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate Oryctolagus cuniculus
K146M K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate Oryctolagus cuniculus
K229A K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate Oryctolagus cuniculus
K229M K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate Oryctolagus cuniculus

Inhibitors

Inhibitors Comment Organism Structure
2,4-Dihydroxybenzaldehyde 4-phosphate
-
 Oryctolagus cuniculus
4-Hydroxybenzaldehyde phosphate competitive Oryctolagus cuniculus
Hydroquinone diphosphate competitive Oryctolagus cuniculus
Resorcinol diphosphate competitive Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate proton-transfer mechanism involving Lys-229, Glu-187 and Lys-146 Oryctolagus cuniculus
a

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate
-
 Oryctolagus cuniculus glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information turnover-numbers of wild-type and mutant enzymes Oryctolagus cuniculus