Literature summary for 4.1.2.10 extracted from

Willeman, W.F.; Gerrits, P.J.; Hanefeld, U.; Brussee, J.; Straathof, A.J.; van der Gen, A.; Heijnen, J.J.
Development of a process model to describe the synthesis of (R)-mandelonitrile by Prunus amygdalus hydroxynitrile lyase in an aqueous-organic biphasic reactor (2002), Biotechnol. Bioeng., 77, 239-247.

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Application

Application	Comment	Organism
synthesis	development and validation of a process model for production of (R)-cyanohydrins in an aqueous-organic biphasic-stirred tank reactor with an unknown interfacial area operated in batch mode. The formation of (R)-mandelonitrile from benzaldehyde and cyanide catalyzed by Prunus amygdalus hydroxynitrile lyase is chosen as a model reaction. Methyl tert-butyl ether is selected as the organic solvent and the reaction conditions are 5°C and pH 5.5 at which the nonenzymatic reaction towards rac-mandelonitrile is largely suppressed	Prunus dulcis

Organism

Organism	UniProt	Comment	Textmining
Prunus dulcis	O24243	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cyanide + benzaldehyde	the formation of (R)-mandelonitrile from benzaldehyde and cyanide catalyzed by Prunus amygdalus hydroxynitrile lyase is chosen as a model reaction for the development and validation of a process model for production of (R)-cyanohydrins in an aqueous-organic biphasic-stirred tank reactor with an unknown interfacial area operated in batch mode. At 5°C and pH 5.5 the nonenzymatic reaction towards rac-mandelonitrile is largely suppressed	Prunus dulcis	(R)-mandelonitrile	-	r

Synonyms

Synonyms	Comment	Organism
PaHNL	-	Prunus dulcis

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Release 2023.1 (January 2023)