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Literature summary for 4.1.1.90 extracted from
- Successful synthesis of active human coagulation factor VII by co-expression of mammalian gamma-glutamyl carboxylase and modification of vit.K cycle in Drosophila Schneider S2 cells (2017), Cytotechnology, 69, 317-327 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | development of expression vectors which enable expressing mammalian gamma-glutamyl carboxylase, vitamin K epoxide reductase complex, subunit 1, and/or PDIA2 along with human coagulation factor VII in Drosophila Schnieder S2 cells. Mammalian GGCX i indispensable to synthesize active factor VII while mammalian vitamin K epoxide reductase complex, subunit 1, and PDIA2 are not critical but supportive factors for S2 cells | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Drosophila Schneider S2 cell | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
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Release 2023.1 (January 2023)
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