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Literature summary for 4.1.1.90 extracted from
- A multiplex assay for detecting genetic variations in CYP2C9, VKORC1, and GGCX involved in warfarin metabolism (2009), Clin. Chem., 55, 823-826.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | multiplexed single nucleotide polymorphism panel (interrogation of the CYP2C9 *2, *3, VKORC1 (-1639G3A), and GGCX (1181T3G) alleles simultaneously) can be successfully used in genotyping of patient blood samples, whereby results can be combined with other clinical parameters in an algorithm for warfarin dosing | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gamma-glutamyl carboxylase | - |
Homo sapiens |
| GGCX | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | genetic variations in GGCX gene contributes to impaired metabolism of warfarin | Homo sapiens |
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Release 2023.1 (January 2023)
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