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Literature summary for 4.1.1.9 extracted from

  • Ussher, J.R.; Lopaschuk, G.D.
    The malonyl CoA axis as a potential target for treating ischaemic heart disease (2008), Cardiovasc. Res., 79, 259-268.
    View publication on PubMed
Search for more literature for 4.1.1.9

Application

Application Comment Organism
medicine MCD is involved in regulating cardiac malonyl-CoA levels, inhibition of MCD can limit rates of fatty acid oxidation, leading to a secondary increase in glucose oxidation associated with an improvement in the functional recovery of the heart during ischaemia/reperfusion injury Mus musculus
medicine MCD is involved in regulating cardiac malonyl-CoA levels, inhibition of MCD can limit rates of fatty acid oxidation, leading to a secondary increase in glucose oxidation associated with an improvement in the functional recovery of the heart during ischaemia/reperfusion injury Homo sapiens
medicine MCD is involved in regulating cardiac malonyl-CoA levels, inhibition of MCD can limit rates of fatty acid oxidation, leading to a secondary increase in glucose oxidation associated with an improvement in the functional recovery of the heart during ischaemia/reperfusion injury Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-
heart
-
 Homo sapiens
-
heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Malonyl-CoA
-
 Mus musculus Acetyl-CoA + CO2
-
 ?
Malonyl-CoA
-
 Homo sapiens Acetyl-CoA + CO2
-
 ?
Malonyl-CoA
-
 Rattus norvegicus Acetyl-CoA + CO2
-
 ?

Synonyms

Synonyms Comment Organism
malonyl CoA decarboxylase
-
 Mus musculus
malonyl CoA decarboxylase
-
 Homo sapiens
malonyl CoA decarboxylase
-
 Rattus norvegicus
MCD
-
 Mus musculus
MCD
-
 Homo sapiens
MCD
-
 Rattus norvegicus