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Literature summary for 4.1.1.76 extracted from

  • Assmann, M.; Muegge, C.; Gassmeyer, S.K.; Enoki, J.; Hilterhaus, L.; Kourist, R.; Liese, A.; Kara, S.
    Improvement of the process stability of arylmalonate decarboxylase by immobilization for biocatalytic profen synthesis (2017), Front. Microbiol., 8, 448 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis by immobilization on an amino C2 acrylate carrier the operational stability of the (S)-selective AMDase variant G74C/M159L/C188G/V43I/A125P/V156L is 158fold increased to a half-life of about 8.6 days. Further optimization is achieved by simple immobilization of the cell lysate Bordetella bronchiseptica

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Bordetella bronchiseptica

Protein Variants

Protein Variants Comment Organism
G74C/M159L/C188G/V43I/A125P/V156l S-selective variant Bordetella bronchiseptica

Organism

Organism UniProt Comment Textmining
Bordetella bronchiseptica Q05115
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aryl-2-methylmalonate
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Bordetella bronchiseptica (2R)-arylpropionate + CO2
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